Products
Our main products
Peptide libraries as novel GPCR ligand candidates designed from human genomic sequence information utilizing PharmaDesign's proprietary bioinformatics.
PharmaDesign searched peptide ligand candidates with one or two disulfide bonds each from the human genome information, and had them chemically synthesized. Because many of known active peptides have disulfide bonds.
PharmaDesign developed new algorithms for prediction of peptide ligand candidates. We searched peptide ligand candidates with one or two disulfide bonds each from the human genome information, and had them chemically synthesized. Because many of known active peptides have disulfide bonds. Only eight sets will be released.
Small-molecule compound libraries focused on GPCRs based on our unique virtual screening technology that have been successful in our contract research business. Target GPCRs is CCR1, CCR2, CCR3, CCR4, CCR5, CCR8 and CX3CR1.
Small-molecule compound libraries focused on GPCRs based on our unique virtual screening technology that have been successful in our contract research business. Target GPCRs is CCR6, CCR9, CCR10, CCR11, CXCR1, CXCR2, CXCR3, CXCR5 and CXCR6.
POODLE (upcoming product)leaflet(PDF)
New
Software to predict disorder regions in proteins. POODLE stands for Prediction Of Order and Disorder by machine LEarning.
POODLE is available online at the CBRC website.
ADMEnsa Interactive™
Comprehensive in silico ADME prediction system (product by BioFocus DPI, in Japan only)
We apply our unique virtual screening technology to our client's drug target protein, from generation to optimization of hit compounds.
Prediction of proteins' functions based on genetic/amino acid sequences
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We predict ORFs from nucleic acid sequences, search homologues and motifs based on amino acid sequences, and predict three-dimensional structures and functions.
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Prediction of proteins' three-dimensional structures
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If your protein has more than 30% homology in amino acid sequence to a protein registered in Protein Data Bank, it is possible to predict its function(s) based on homology modeling. In addition, if your protein has cSNP within its protein coding regions, it will help to understand how the mutation would affect its three-dimensional structure.
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Alternative splicing variants (ASVs) search
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Our analysis clarifies a target gene's exon-intron structure based on genomic sequence, mRNA sequence (major form) and amino acid sequence. We search mRNA containing the exons and introns from human EST database, and make them candidates for ASV. In order to avoid overlapping with known ASVs, we double-check with patent databases (nucleic acid and amino acid sequences) and other databases such as RefSeq.
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